Nanoparticle-based theranostics agents have emerged as a promising approach in modern hospitals, offering integrated solutions for disease diagnosis and therapy. Among the various types of materials investigated for theranostics applications, holmium nanoparticles (HoNPs) have gained significant attention due to their advantageous magnetic, optical, and chemical properties. Therefore, this review aims to explore synthesis, functionalization, and theranostic prospects of HoNPs. Synthesis approach, including polyol, precipitation, thermal decomposition, and solvothermal, was extensively discussed. Nanoparticles properties (such as size, shape, and morphology), relativity value, biodistribution, and cytotoxicity were also discussed. Materials for surface functionalization were explored to broaden the applications and improve functionality of HoNPs. In addition, therapeutic and diagnostic applications of HoNPs were examined, comprising Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) contrast enhancement, drug delivery, and radiotherapy.
Contributes to the following SDGs:
Access to document: https://doi.org/10.1016/j.rsurfi.2025.100545
By Fauzia et al.
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, Indonesia.
Study Center of Sensor and Green Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Bandung 40132, Indonesia.
#UnpadResearch #Goodhealthandwellbeing #SDGs3 #Holmium #ContrastAgents
02/Kim/2025
