Aglaia pachyphylla is a species from the Aglaia genus (Meliaceae) and the chemical constituent has not been widely explored. A new cycloartane-type triterpenoid, pachyphyllanone (1), along with four known compounds (2–5) were isolated from Aglaia pachyphylla Miq. Furthermore, the structure of the new compound was elucidated by the interpretation of spectroscopic data, including 1D and 2D-NMR, as well as ECD and NMR calculations (DP4+ analysis). Compounds 1–5 showed cytotoxic activities against MCF-7 with IC50 values ranging from 160.74 to 299.75 μM.
Contributes to the following SDGs:
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Access to document: https://doi.org/10.1080/10286020.2024.2446280
By Safriansyah et al.
*correspondence author: [email protected]
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, Indonesia.
#UnpadResearch #GoodHealthandWellBeing #SDGs3 #AglaiaPachyphylla #Meliaceae #MCF-7
17/Kim/2025
