Mitochondrial DNA (mtDNA) mutations can impair oxidative phosphorylation and ATP production, potentially contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). This study aimed to investigate the relationship between mtDNA mutations and ATP levels in blood and urine samples…
Lime peel essential oil (LPO) exhibits promising antibacterial properties, yet its inherent instability limits its practical applications, necessitating effective encapsulation strategies. Microencapsulation provides protection and facilitates the controlled release of active compounds. This study developed LPO microcapsules via complex coacervation, employing gum arabic and gelatin as…
The onoceranoid triterpenes isolated from the kokossan fruit peels were studied in vitro using MCF-7 breast cancer cells. Three onoceranoids, namely 8,14-secogammacera-8(26),14-dien–3,21-diol (1), 3β-hydroxyonocera-8(26),14-dien-21-one (2) and α,γ-onoceradienedione (3), were obtained from the ethyl acetate extract of kokossan fruit peels. Compounds 1 –…
A research team from Universitas Padjadjaran, Indonesia, led by Widya Norma Insani, PhD (Department of Pharmacology and Clinical Pharmacy; Centre of Excellence for Pharmaceutical Care Innovation), together with Neily Zakiyah, PhD, Irma Melyani Puspitasari, Prof Dr, Muhammad Yorga Permana, PhD…